Estados financieros detallados de Amicus Therapeutics, Inc. (FOLD): cuenta de resultados, balance general y flujo de caja. Sigue la evolución de márgenes, deuda, liquidez y rentabilidad año a año con hasta 20 años de histórico.
Resumen del Análisis
Amicus Therapeutics, Inc. registró ingresos de $634.2M en el último ejercicio fiscal, con un CAGR de 5 años del 19.4%.
Márgenes de los últimos 12 meses: margen bruto 87.9%, margen operativo 5.2%, margen neto -4.3%.
Cuenta de Resultados (10 años)
| Año | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| Ingresos | $5.0M | $36.9M | $91.2M | $182.2M | $260.9M | $305.5M | $329.2M | $399.4M | $528.3M | $634.2M |
| Coste de Ventas | $833000 | $6.2M | $14.4M | $22.0M | $31.0M | $34.5M | $38.6M | $37.3M | $52.9M | $80.4M |
| Beneficio Bruto | $4.1M | $30.7M | $76.8M | $160.3M | $229.8M | $271.0M | $290.6M | $362.0M | $475.4M | $553.8M |
| I+D | $104.8M | $149.3M | $270.9M | $286.4M | $308.4M | $272.0M | $276.7M | $152.4M | $109.4M | $135.8M |
| Generales y Administrativos | $71.2M | $88.7M | $127.2M | $169.9M | $156.4M | $192.7M | $213.0M | $275.3M | $323.4M | $383.5M |
| Gastos Operativos | $179.2M | $241.6M | $402.3M | $464.3M | $476.8M | $477.5M | $502.8M | $439.2M | $450.5M | $519.3M |
| Beneficio Operativo | -$181.9M | -$442.0M | -$328.8M | -$304.0M | -$247.0M | -$206.4M | -$212.1M | -$77.2M | $24.9M | $34.5M |
| EBITDA | -$195.1M | -$428.3M | -$322.5M | -$332.3M | -$243.0M | -$202.9M | -$199.6M | -$92.1M | $29.4M | $53.8M |
| Gastos por Intereses | $5.4M | $17.2M | $22.4M | $18.9M | $22.4M | $32.5M | $37.1M | $50.1M | $49.6M | $46.2M |
| Beneficio Antes de Impuestos | -$203.8M | -$449.1M | -$349.1M | -$355.9M | -$274.3M | -$241.6M | -$242.0M | -$150.1M | -$28.8M | $191000 |
| Impuestos | -$3.7M | -$165.1M | -$94000 | $478000 | $2.6M | $8.9M | -$5.5M | $1.5M | $27.4M | $27.3M |
| Beneficio Neto | -$200.0M | -$284.0M | -$349.0M | -$356.4M | -$276.9M | -$250.5M | -$236.6M | -$151.6M | -$56.1M | -$27.1M |
| BPA | $-1.49 | $-1.85 | $-1.88 | $-1.48 | $-1.07 | $-0.92 | $-0.82 | $-0.51 | $-0.18 | $-0.09 |
| BPA Diluido | $-1.49 | $-1.85 | $-1.88 | $-1.48 | $-1.07 | $-0.92 | $-0.82 | $-0.51 | $-0.18 | $-0.09 |
| Acciones en Circulación (Diluidas) | $134.4M | $153.4M | $185.8M | $240.4M | $258.9M | $271.4M | $289.1M | $295.2M | $304.4M | $308.4M |
Cuenta de Resultados (Trimestral)
| Año | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 |
|---|
| Ingresos | $125.2M | $154.7M | $169.1M | $185.2M |
| Beneficio Bruto | $113.6M | $139.5M | $147.7M | $156.8M |
| Beneficio Operativo | -$8.0M | -$9.5M | $34.3M | $15.9M |
| EBITDA | -$4.8M | -$5.8M | $47.9M | $16.5M |
| Beneficio Neto | -$21.7M | -$24.4M | $17.3M | $1.7M |
| BPA | $-0.07 | $-0.08 | $0.06 | $0.01 |
| BPA Diluido | $-0.07 | $-0.08 | $0.06 | $0.01 |
Balance (10 años)
| Año | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| Caja y Equivalentes | $187.0M | $49.1M | $79.7M | $142.8M | $163.2M | $245.2M | $148.8M | $247.0M | $213.8M | $214.0M |
| Inversiones a Corto | $143.3M | $309.5M | $424.4M | $309.9M | $320.0M | $237.3M | $144.8M | $39.2M | $36.2M | $79.5M |
| Cuentas por Cobrar | $1.3M | $9.5M | $22.0M | $33.3M | $46.9M | $52.7M | $66.2M | $87.6M | $101.1M | $115.3M |
| Inventario | $3.4M | $4.6M | $8.4M | $14.0M | $19.6M | $26.8M | $23.8M | $59.7M | $118.8M | $228.8M |
| Activos Corrientes | $340.1M | $392.0M | $551.1M | $520.1M | $579.5M | $596.8M | $423.8M | $483.1M | $504.7M | $676.2M |
| Inmovilizado Material | $9.8M | $9.1M | $11.4M | $81.0M | $67.2M | $63.1M | $60.3M | $58.0M | $51.7M | $48.2M |
| Fondo de Comercio | $197.8M | $197.8M | $197.8M | $197.8M | $197.8M | $197.8M | $197.8M | $197.8M | $197.8M | $197.8M |
| Activos Intangibles | $486.7M | $23.0M | $23.0M | $23.0M | $23.0M | $23.0M | $23.0M | $20.5M | $17.2M | $13.9M |
| Activos Totales | $1.04B | $627.0M | $790.0M | $850.2M | $886.5M | $905.1M | $724.2M | $777.9M | $785.0M | $949.9M |
| Cuentas por Pagar | $12.9M | $7.9M | $6.6M | $21.7M | $17.1M | $21.5M | $15.4M | $15.1M | $12.9M | $28.6M |
| Deuda a Corto | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | $8.7M |
| Pasivos Corrientes | $111.0M | $70.0M | $86.1M | $128.8M | $129.7M | $146.0M | $139.0M | $167.7M | $148.7M | $237.8M |
| Deuda a Largo | $154.5M | $164.2M | $321.7M | $149.5M | $389.3M | $389.4M | $392.0M | $387.9M | $390.1M | $433.6M |
| Pasivos Totales | $676.7M | $274.2M | $447.0M | $373.8M | $600.1M | $597.8M | $601.1M | $617.7M | $591.0M | $675.6M |
| Reservas | -$779.6M | -$1.06B | -$1.41B | -$1.77B | -$2.05B | -$2.30B | -$2.53B | -$2.68B | -$2.74B | -$2.77B |
| Patrimonio Neto | $360.2M | $352.9M | $342.9M | $476.4M | $286.4M | $307.4M | $123.0M | $160.2M | $194.0M | $274.2M |
| Deuda Total | $154.5M | $164.5M | $321.7M | $210.2M | $441.7M | $440.1M | $452.1M | $445.1M | $443.6M | $483.3M |
| Deuda Neta | -$175.9M | -$194.1M | -$182.4M | -$242.5M | -$41.5M | -$42.4M | $158.5M | $158.9M | $193.7M | $189.8M |
| Capital Circulante | $229.1M | $321.9M | $465.0M | $391.3M | $449.8M | $450.9M | $284.8M | $315.4M | $356.0M | $438.3M |
Balance (Trimestral)
| Año | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 |
|---|
| Caja y Equivalentes | $181.7M | $158.7M | $190.6M | $214.0M |
| Activos Totales | $789.8M | $815.3M | $868.8M | $949.9M |
| Pasivos Totales | $596.3M | $611.0M | $638.4M | $675.6M |
| Patrimonio Neto | $193.6M | $204.3M | $230.4M | $274.2M |
| Deuda Total | $443.5M | $443.3M | $442.8M | $483.3M |
Flujo de Caja (10 años)
| Año | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| Beneficio Neto | -$200.0M | -$284.0M | -$349.0M | -$356.4M | -$276.9M | -$250.5M | -$236.6M | -$151.6M | -$56.1M | -$27.1M |
| Amortizaciones | $3.2M | $3.6M | $4.2M | $4.8M | $8.8M | $6.2M | $5.3M | $7.9M | $8.5M | $2.6M |
| Compensación en Acciones | $17.5M | $23.1M | $29.3M | $44.4M | $49.2M | $57.8M | $76.5M | $86.1M | $84.9M | $87.4M |
| Cambio en Capital Circulante | $1.1M | -$25.8M | -$4.7M | $11.6M | -$32.1M | -$18.6M | -$39.9M | -$48.0M | -$98.9M | -$39.6M |
| Flujo de Caja Operativo | -$150.5M | -$215.5M | -$300.0M | -$250.4M | -$233.3M | -$202.5M | -$166.6M | -$69.1M | -$33.9M | $33.1M |
| Inversiones (CapEx) | -$6.0M | -$4.5M | -$6.3M | -$20.0M | -$3.2M | -$3.9M | -$3.8M | -$7.4M | -$3.6M | -$3.3M |
| Adquisiciones | 0 | 0 | $6.3M | 0 | 0 | 0 | $3.4M | 0 | 0 | 0 |
| Recompra de Acciones | -$1.3M | -$1.6M | -$2.8M | 0 | 0 | 0 | -$11.5M | 0 | 0 | 0 |
| Dividendos Pagados | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Flujo de Caja Libre | -$156.5M | -$220.0M | -$306.3M | -$270.4M | -$236.5M | -$206.4M | -$170.3M | -$76.5M | -$37.4M | $29.8M |
Flujo de Caja (Trimestral)
| Año | 2025-Q1 | 2025-Q2 | 2025-Q3 | 2025-Q4 |
|---|
| Flujo de Caja Operativo | $7.8M | -$26.5M | $35.7M | $16.3M |
| Inversiones (CapEx) | -$212000 | -$2.4M | -$382000 | -$299000 |
| Flujo de Caja Libre | $7.5M | -$28.9M | $35.3M | $16.0M |
| Dividendos Pagados | 0 | 0 | 0 | 0 |
| Compensación en Acciones | $25.2M | $17.6M | $18.1M | $26.6M |
Crecimiento y Márgenes (10 años)
| Año | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| Crecimiento Ingresos (anual) | | +644.9% | +147.1% | +99.7% | +43.2% | +17.1% | +7.8% | +21.3% | +32.3% | +20.0% |
| Crecimiento Beneficio Neto (anual) | | -42.0% | -22.9% | -2.1% | +22.3% | +9.5% | +5.5% | +35.9% | +63.0% | +51.7% |
| Crecimiento BPA (anual) | | -24.2% | -1.6% | +21.3% | +27.7% | +14.0% | +10.9% | +37.8% | +64.7% | +51.2% |
| Cambio en Acciones (anual) | | +14.1% | +21.2% | +29.4% | +7.7% | +4.8% | +6.5% | +2.1% | +3.1% | +1.3% |
| Crecimiento FCF (anual) | | -40.6% | -39.2% | +11.7% | +12.5% | +12.7% | +17.5% | +55.1% | +51.1% | +179.7% |
| Margen Bruto | 83.2% | 83.1% | 84.2% | 87.9% | 88.1% | 88.7% | 88.3% | 90.7% | 90.0% | 87.3% |
| Margen Operativo | -3668.6% | -1196.8% | -360.3% | -166.8% | -94.7% | -67.6% | -64.4% | -19.3% | 4.7% | 5.4% |
| Margen EBITDA | -3935.9% | -1159.7% | -353.4% | -182.3% | -93.1% | -66.4% | -60.6% | -23.1% | 5.6% | 8.5% |
| Margen Neto | -4034.7% | -769.0% | -382.5% | -195.6% | -106.1% | -82.0% | -71.9% | -38.0% | -10.6% | -4.3% |
| Margen FCF | -3156.2% | -595.8% | -335.6% | -148.4% | -90.7% | -67.6% | -51.7% | -19.2% | -7.1% | 4.7% |
| Tasa Impositiva Efectiva | 1.8% | 36.8% | 0.0% | -0.1% | -0.9% | -3.7% | 2.3% | -1.0% | -95.1% | 14293.7% |
Datos por Acción (10 años)
| Año | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| FCF por Acción | $-1.16 | $-1.43 | $-1.65 | $-1.12 | $-0.91 | $-0.76 | $-0.59 | $-0.26 | $-0.12 | $0.10 |
| Dividendo por Acción | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 |
| Acciones en Circulación (Básicas) | $134.4M | $153.4M | $185.8M | $240.4M | $258.9M | $271.4M | $289.1M | $295.2M | $304.4M | $308.4M |
Qué mirar en Biotech
La mayoría de biotechs pequeñas pierden dinero. Analizarlas con P/E no tiene sentido — mira caja y pipeline.
- Cash Runway — Meses de caja al ritmo de gasto actual. <18 meses = riesgo de dilución urgente
- Cash burn anual — Ritmo al que queman caja operativa. Comparar con posición de caja para proyectar runway
- Total Debt — Biotech sin ingresos + deuda = receta para bancarrota
- I+D / Capitalización — Cuánto invierten en pipeline vs lo que vale la empresa — indicador de intensidad investigadora
- Market cap / Cash — Si cotiza cerca de su caja, el mercado le da ~0 valor al pipeline — puede ser oportunidad o trampa
Rentabilidad
| Margen bruto | 87.91% |
| Margen operativo | 5.17% |
| Margen neto | -4.27% |
Salud financiera
| Deuda / Patrimonio | 1.76 |
| Ratio corriente | 2.84 |
Ratios Clave (10 años)
| Año | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| P/E | -3.34 | -7.78 | -5.10 | -6.58 | -21.58 | -12.55 | -14.89 | -27.82 | -52.33 | -162.00 |
| P/VC | 1.85 | 6.25 | 5.19 | 4.92 | 20.87 | 10.20 | 28.68 | 26.15 | 14.78 | 16.01 |
| P/V | 134.73 | 59.76 | 19.51 | 12.85 | 22.91 | 10.26 | 10.72 | 10.49 | 5.43 | 6.92 |
| Margen Bruto | 83.2% | 83.1% | 84.2% | 87.9% | 88.1% | 88.7% | 88.3% | 90.7% | 90.0% | 87.3% |
| Margen Operativo | -3668.6% | -1196.8% | -360.3% | -166.8% | -94.7% | -67.6% | -64.4% | -19.3% | 4.7% | 5.4% |
| Margen Neto | -4034.7% | -769.0% | -382.5% | -195.6% | -106.1% | -82.0% | -71.9% | -38.0% | -10.6% | -4.3% |