Merck vs Pfizer: stock comparison

Analysis: · Data: companies' official filings · Updated

Merck or Pfizer: which stock is cheaper in 2026?

As of October 5, 2026, Merck (MRK) trades at 115× earnings (P/E) and Pfizer (PFE) at 36.7×, according to Kaplio. The median across the 157 pharma companies above $2bn in Kaplio's universe is 27.5×. A caveat on Merck: its earnings over the last twelve months are far from what the consensus expects, so its current P/E is not representative. A caveat on Pfizer: its earnings over the last twelve months are far from what the consensus expects, so its current P/E is not representative.

According to the Kaplio Summary

The same verdict as each company's page: price range by multiples, the four lights, the expected return if consensus is right and what Buffett and Lynch would say today.

Merck (MRK)Pfizer (PFE)
Summary valuationfairly priced ($193–$261)no verdict ($80)
The four lightsValuation: P/E 115.4× (fairly priced)
Business: ROIC 6 % (weak)
Balance sheet: Net debt/EBITDA 1.3× (solid)
Results: 7 of 8 (on track)
Valuation: P/E 36.6× (no verdict)
Business: ROIC 9 % (fair)
Balance sheet: Net debt/EBITDA 4.4× (fragile)
Results: 8 of 8 (on track)
Expected return (per year)+7.4 % a year (to 2028)—
Buffett methodquality 81 · would waitquality 68 · would not approve
Lynch methodstalwart · would waitturnaround · approves

How it is computed

Metrics side by side

MetricMerck (MRK)Pfizer (PFE)
Overview
Market Cap$356B$158B
Price$144.30$27.80
Valuation
P/E115×36.7×
P/B8.2×1.8×
P/S5.2×2.5×
EV/EBITDA29.1×17.3×
FCF Yield4.5 %7.0 %
Dividend Yield2.4 %6.2 %
Profitability
ROIC6.0 %9.0 %
ROE6.6 %4.9 %
Gross Margin75.4 %71.3 %
Operating Margin16.7 %25.1 %
Net Margin4.8 %6.8 %
Growth
Revenue 5Y CAGR9.4 %8.5 %
EPS 5Y CAGR21.2 %-3.8 %
FCF 5Y CAGR16.2 %-4.8 %
Balance Sheet
Net Debt / EBITDA1.3×4.4×
Debt / Equity1.3×0.7×

Trailing twelve months where available; otherwise the latest fiscal year. Growth: five-year compound annual rate.

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