Kiniksa Pharmaceuticals International, plc (KNSA) Valuation — DCF, Graham & Comparables

Kiniksa Pharmaceuticals International, plc (KNSA) — Price $93.29 (closing price, November 3, 2026) — Healthcare — Medical - Pharmaceuticals — NASDAQ

Latest reported results:

Valuation dashboard for Kiniksa Pharmaceuticals International, plc (KNSA) with P/E 71.21, P/B 10.27, EV/EBITDA 49.0 and dividend yield 0.00%. DCF, Graham Number, EPS growth, peer multiples and dividend discount models plus sector comparison against other Healthcare companies.

Kiniksa Pharmaceuticals International, plc, a biopharmaceutical company, develops and commercializes medical therapies in the United States, the United Kingdom, and internationally. The company offers ARCALYST, an interleukin-1alpha and 1beta cytokine trap for the treatment of recurrent pericarditis, a chronic autoinflammatory cardiovascular disease and cardiac sarcoidosis.

What would it be worth at its usual multiples?

Versus its usual multiples: expensive · Current P/E 71.2× · Multiples range: $40.20 · $40.20.

At its sector median (30.7×) $40 (-57 %). Implied price from applying the reference multiples to today's earnings (or book value, or FFO) per share. Not a fair value: it is where the stock would trade at its usual multiples.

P/E calculated by Kaplio with 12-month GAAP earnings; the data provider reports 87.2×.

Analysis Summary

Trailing-twelve-month margins: gross margin 54.3%, operating margin 13.8%, net margin 11.6%.

At $93.29 (closing price, November 3, 2026), KNSA trades at a P/E of 71.21 and an ROE of 17.27%. Market capitalisation stands at $7.3B.

Balance sheet quality for KNSA: debt-to-equity ratio of 0.01, current ratio of 3.91 over the last 12 months. A debt-to-equity below 1.0 typically signals conservative capital structure, while a current ratio above 1.5 indicates comfortable short-term liquidity.

Valuation Ratios

P/E Ratio71.21
Price / Book10.27
EV / EBITDA49.0
Dividend Yield0.00%

Peer Comparison

SymbolCompanyMarket CapP/EP/BROE
KNSAKiniksa Pharmaceuticals International, plc$7.3B71.2110.2717.3%
IMVTImmunovant, Inc.$6.0B8.12-69.6%
DNTHDianthus Therapeutics, Inc.$4.6B3.95-3.5%
SYRESpyre Therapeutics, Inc.$9.2B32.67-29.8%
ORKAOruka Therapeutics, Inc.$6.6B5.62-20.8%
NRIXNurix Therapeutics, Inc.$2.8B11.182.9749.3%

Price

Price$93.29 (closing price, November 3, 2026)
Market Cap$7.3B
ExchangeNASDAQ
CountryGB

Profitability

Return on Equity17.27%
Return on Invested Capital12.30%
Return on Assets11.14%
Gross Margin54.26%
Operating Margin13.79%
Net Margin11.58%

Related companies: IMVT · DNTH · SYRE · ORKA · NRIX

Explore sector: Healthcare · Medical - Pharmaceuticals

More sections of KNSA: Overview · Financials · Statistics · Estimates · Technical · Ownership · News · Events

Discover more: Weekly Radar: the S&P 500 through the Buffett and Lynch methods · Companies that pass the Buffett method · Companies that pass the Lynch method · Stocks that pass Graham's defensive investor test today · Investment Academy — learn to analyze stocks