NuCana plc (NCNA) is a publicly traded company in the Healthcare — Biotechnology industry listed on NASDAQ. This overview shows the latest price, key valuation ratios, profitability metrics and financial-health indicators used by fundamental investors.
NuCana plc is a clinical-stage biopharmaceutical firm dedicated to pioneering advanced therapies for oncology. Its innovative product pipeline is underpinned by a proprietary ProTide technology platform.
Analysis Summary
Trailing-twelve-month margins: gross margin 0.0%, operating margin 0.0%, net margin 0.0%.
At the current price of $1.30, NCNA has negative trailing earnings (P/E not meaningful) and an ROE of -120.66%. Market capitalisation stands at $8M.
Balance sheet quality for NCNA: current ratio of 5.6, net cash position of $23.6M. A debt-to-equity below 1.0 typically signals conservative capital structure, while a current ratio above 1.5 indicates comfortable short-term liquidity.
Price
| Price | $1.30 |
| Market Cap | $8M |
| Exchange | NASDAQ |
| Country | GB |
Valuation Ratios
| Price / Book | 0.23 |
| EV / EBITDA | 0.85 |
| Dividend Yield | 0.00% |
Profitability
| Return on Equity | -120.66% |
| Return on Invested Capital | -77.17% |
| Return on Assets | -98.39% |
| Gross Margin | 0.00% |
| Operating Margin | 0.00% |
| Net Margin | 0.00% |
Financial Health
| Debt / Equity | 0.03 |
| Current Ratio | 5.60 |
| Piotroski F-Score | 3 |
| Altman Z-Score | -12.10 |
What to look at in Biotech
Most small biotechs lose money. Analysing them with P/E makes no sense — look at cash and pipeline.
- Cash Runway — Months of cash at current burn rate. <18 months = urgent dilution risk
- Annual cash burn — Rate at which they burn operating cash. Compare with cash position to project runway
- Total Debt — Biotech with no revenue + debt = recipe for bankruptcy
- R&D / Market cap — How much they invest in pipeline vs the company value — research-intensity indicator
- Market cap / Cash — If it trades near its cash, the market assigns ~0 value to the pipeline — opportunity or trap
Peer Comparison
| Symbol | Company | Market Cap | P/E | P/B | ROE |
|---|---|---|---|---|---|
| NCNA | NuCana plc | $8M | 0.23 | -120.7% | |
| 0QZU.L | Vertex Pharmaceuticals Incorporated | $131.8B | |||
| VRTX | Vertex Pharmaceuticals Incorporated | $130.3B | 29.68 | 6.45 | 23.3% |
| 0R2M.L | Regeneron Pharmaceuticals, Inc. | $84.0B | |||
| REGN | Regeneron Pharmaceuticals, Inc. | $79.8B | 18.79 | 2.57 | 13.8% |
| ARGX | argenx SE | $61.2B | 36.30 | 7.40 | 21.7% |
| MRNA | Moderna, Inc. | $57.8B | 1.34 | -39.2% | |
| RVMD | Revolution Medicines, Inc. | $41.7B | 15.96 | -96.4% |
Price Performance
| 1 month | -14.47% |
| 3 months | -31.94% |
| Year-to-date | -63.89% |
| 1 year | -67.17% |
| 3 years | -99.96% |
| 5 years | -99.99% |
52-Week Range
| 52-week High | $7.22 |
| 52-week Low | $1.21 |
| Avg Volume (90d) | 59K |
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Explore sector: Healthcare · Biotechnology
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