BeOne Medicines AG (ONC) Valuation — DCF, Graham & Comparables

BeOne Medicines AG (ONC) — Price $377.63 (closing price, October 28, 2026) — Healthcare — Biotechnology — NASDAQ

Latest reported results:

Valuation dashboard for BeOne Medicines AG (ONC) with P/E 5.22, P/B 10.68, EV/EBITDA 32.02 and dividend yield 0.00%. DCF, Graham Number, EPS growth, peer multiples and dividend discount models plus sector comparison against other Healthcare companies.

BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company’s commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton’s Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult...

Analysis Summary

BeOne Medicines AG reported revenue of $5.34B in the most recent fiscal year, growing at a 5-year CAGR of 76.8%.

Trailing-twelve-month margins: gross margin 87.8%, operating margin 15.1%, net margin 10.7%.

At $377.63 (closing price, October 28, 2026), ONC trades at a P/E of 5.22 and an ROE of 14.27%. Market capitalisation stands at $40.4B, placing it among large-cap names.

Balance sheet quality for ONC: current ratio of 3.4. A debt-to-equity below 1.0 typically signals conservative capital structure, while a current ratio above 1.5 indicates comfortable short-term liquidity.

Valuation Ratios

P/E Ratio5.22
Price / Book10.68
EV / EBITDA32.02
Dividend Yield0.00%

Valuation Models

DCF Fair Value$-3,580.02
vs Current Price-1,048.0%

Peer Comparison

SymbolCompanyMarket CapP/EP/BROE
ONCBeOne Medicines AG$40.4B5.2210.6814.3%
VRTXVertex Pharmaceuticals Incorporated$134.3B30.836.6423.3%
0QZU.LVertex Pharmaceuticals Incorporated$134.0B30.256.5723.3%
0R2M.LRegeneron Pharmaceuticals, Inc.$86.5B19.222.6213.8%
MRNAModerna, Inc.$85.5B12.54-39.2%
REGNRegeneron Pharmaceuticals, Inc.$83.7B20.122.6513.8%
ARGXargenx SE$54.7B41.716.6116.9%
0QNO.LLonza Group AG$43.8B5.43-1.3%

Price

Price$377.63 (closing price, October 28, 2026)
Market Cap$40.4B
ExchangeNASDAQ
CountryCH

Profitability

Return on Equity14.27%
Return on Invested Capital9.63%
Return on Assets7.17%
Gross Margin87.82%
Operating Margin15.05%
Net Margin10.68%

Related companies: VRTX · 0QZU.L · 0R2M.L · MRNA · REGN · ARGX · 0QNO.L · RVMD

Explore sector: Healthcare · Biotechnology

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