Valuation dashboard for Oruka Therapeutics, Inc. (ORKA) with P/E N/A, P/B 5.62, EV/EBITDA -42.7 and dividend yield 0.00%. DCF, Graham Number, EPS growth, peer multiples and dividend discount models plus sector comparison against other Healthcare companies.
Oruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications.
Analysis Summary
Trailing-twelve-month margins: gross margin 0.0%, operating margin 0.0%, net margin 0.0%.
At $99.55 (closing price, November 3, 2026), ORKA has negative trailing earnings (P/E not meaningful) and an ROE of -20.76%. Market capitalisation stands at $6.6B.
Balance sheet quality for ORKA: debt-to-equity ratio of 0.00, current ratio of 38.51 over the last 12 months. A debt-to-equity below 1.0 typically signals conservative capital structure, while a current ratio above 1.5 indicates comfortable short-term liquidity.
Valuation Ratios
| Price / Book | 5.62 |
| EV / EBITDA | -42.7 |
| Dividend Yield | 0.00% |
Peer Comparison
| Symbol | Company | Market Cap | P/E | P/B | ROE |
|---|---|---|---|---|---|
| ORKA | Oruka Therapeutics, Inc. | $6.6B | 5.62 | -20.8% | |
| DNTH | Dianthus Therapeutics, Inc. | $4.6B | 3.95 | -3.5% | |
| XNCR | Xencor, Inc. | $2.3B | 4.62 | -28.7% | |
| VRTX | Vertex Pharmaceuticals Incorporated | $134.5B | 34.15 | 6.44 | 20.1% |
| 0QZU.L | Vertex Pharmaceuticals Incorporated | $134.0B | 30.25 | 6.57 | 23.3% |
| REGN | Regeneron Pharmaceuticals, Inc. | $100.2B | 21.51 | 2.96 | 15.1% |
| MRNA | Moderna, Inc. | $91.2B | 13.38 | -39.2% | |
| 0R2M.L | Regeneron Pharmaceuticals, Inc. | $86.5B | 19.22 | 2.62 | 13.8% |
Price
| Price | $99.55 (closing price, November 3, 2026) |
| Market Cap | $6.6B |
| Exchange | NASDAQ |
| Country | US |
Profitability
| Return on Equity | -20.76% |
| Return on Invested Capital | -13.88% |
| Return on Assets | -11.66% |
| Gross Margin | 0.00% |
| Operating Margin | 0.00% |
| Net Margin | 0.00% |
Related companies: DNTH · XNCR · VRTX · 0QZU.L · REGN · MRNA · 0R2M.L · ARGX
Explore sector: Healthcare · Biotechnology
More sections of ORKA: Overview · Financials · Statistics · Estimates · Technical · Ownership · News · Events
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