Spyre Therapeutics, Inc. (SYRE) Technical Analysis & Indicators

Spyre Therapeutics, Inc. (SYRE) — Price $99.27 (closing price, November 3, 2026) — Healthcare — Biotechnology — NASDAQ

Latest reported results:

Technical analysis of Spyre Therapeutics, Inc. (SYRE): price and volume charts, candlestick patterns, moving averages (SMA, EMA), RSI, MACD, ADX and Bollinger Bands. Identify momentum, trend direction and potential entry/exit zones.

Spyre Therapeutics, Inc. is a biotechnology firm operating at the preclinical stage, dedicated to creating innovative treatments for individuals afflicted with inflammatory bowel disease (IBD). Among its pipeline candidates is SPY001, a human monoclonal immunoglobulin G1 antibody specifically engineered to target and bind with the a4ß7 integrin. This particular therapy is under development for addressing both ulcerative colitis and Crohn's disease, two forms of IBD.

Price Performance

1 month+3.01%
3 months-7.65%
Year-to-date+191.54%
1 year+315.62%
3 years+744.47%
5 years-47.81%
10 years-37.58%

52-Week Range

52-week High$110.18
52-week Low$21.15
Avg Volume (90d)1.2M

Technical Indicators

SMA 50$89.84
SMA 200$73.54
Beta2.94
30-day Volatility (annualised)67.1%
Price vs SMA 50+6.3%
Price vs SMA 200+29.9%

Monthly Close (12 months)

MonthCloseChange
2025-12$32.76
2026-01$31.98-2.4%
2026-02$43.01+34.5%
2026-03$50.44+17.3%
2026-04$74.45+47.6%
2026-05$73.50-1.3%
2026-06$88.78+20.8%
2026-07$98.33+10.8%
2026-08$89.33-9.2%
2026-09$89.03-0.3%
2026-10$96.56+8.5%
2026-11$95.51-1.1%

Upcoming Earnings

DateEPS Est.Revenue Est.
2026-11-03$-0.79
2026-08-04$-0.76
2026-05-05$-0.66
2026-02-19$-0.66$143M
2025-11-04$-0.76$2M
2025-08-05$-0.73

Price

Price$99.27 (closing price, November 3, 2026)
Market Cap$9.2B
ExchangeNASDAQ
CountryUS

Valuation Ratios

Price / Book32.67
Dividend Yield0.00%

Financial Health

Debt / Equity0.00
Current Ratio27.40
Piotroski F-Score2
Altman Z-Score18.32

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Explore sector: Healthcare · Biotechnology

More sections of SYRE: Overview · Financials · Valuation · Statistics · Estimates · Ownership · News · Events

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